{"id":85,"date":"2020-08-26T10:10:11","date_gmt":"2020-08-26T10:10:11","guid":{"rendered":"https:\/\/www.reusceltumor-cumcura.be\/?page_id=85"},"modified":"2026-05-25T14:45:05","modified_gmt":"2026-05-25T14:45:05","slug":"algemeen","status":"publish","type":"page","link":"https:\/\/www.reusceltumor-cumcura.be\/en\/algemeen\/","title":{"rendered":"General"},"content":{"rendered":"<div class=\"et_pb_section_0 et_pb_section et_section_regular et_block_section section_has_divider et_pb_bottom_divider\"><div class=\"et_pb_row_0 et_pb_row et_block_row\"><div class=\"et_pb_column_0 et_pb_column et_pb_column_1_2 et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_animated et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h1>General<\/h1>\n<\/div><\/div><\/div><div class=\"et_pb_column_1 et_pb_column et_pb_column_1_2 et-last-child et_block_column et_pb_column_empty et_pb_css_mix_blend_mode_passthrough\"><\/div><\/div><div class=\"et_pb_bottom_inside_divider et-no-transition\"><\/div><\/div><div class=\"et_pb_section_1 et_pb_section et_section_specialty et_pb_gutters3 et_block_section\"><div class=\"et_pb_row et_pb_row-1-4_3-4 et_block_row\"><div class=\"et_pb_column_2 et_pb_column et_pb_column_single et_pb_column_1_4 et_block_column et_pb_css_mix_blend_mode_passthrough stickybar\"><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_0_wrapper\"><a class=\"et_pb_button_0 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"\/en\/overzicht\/\">Overview<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_1_wrapper\"><a class=\"et_pb_button_1 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"\/en\/algemeen\/\">General<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_2_wrapper\"><a class=\"et_pb_button_2 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#watissarcoma\">What is a giant cell tumour?<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_3_wrapper\"><a class=\"et_pb_button_3 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#watisreusceltumorbot\">What is a giant cell tumour of the bone?<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_4_wrapper\"><a class=\"et_pb_button_4 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#watisreusceltumorwekedelen\">What is a giant soft tissue cell tumour?<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_5_wrapper\"><a class=\"et_pb_button_5 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#waarenbijwie\">Where and in whom does it occur?<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_6_wrapper\"><a class=\"et_pb_button_6 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#watisdeoorzaak\">What is the cause?<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_7_wrapper\"><a class=\"et_pb_button_7 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"#klachten\">What symptoms does it cause? <\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_8_wrapper\"><a class=\"et_pb_button_8 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"\/en\/diagnose\/\">Diagnosis<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_9_wrapper\"><a class=\"et_pb_button_9 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"\/en\/behandeling\/\">Treatment<\/a><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_10_wrapper\"><a class=\"et_pb_button_10 et_pb_button et_pb_bg_layout_dark et_pb_module et_block_module\" href=\"\/en\/ondersteuning\/\">Support<\/a><\/div><\/div><div class=\"et_pb_column_3 et_pb_column et_pb_specialty_column et_pb_column_3_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_row_inner_0 et_pb_row_inner et_block_row\" id=\"watissarcoma\"><div class=\"et_pb_column_inner_0 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_1 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\" id=\"#toggle1\"><div class=\"et_pb_text_inner\"><h2>What is a giant cell tumour?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_0 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><div class=\"et_pb_text_2 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p><span data-contrast=\"auto\">A\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0is a tumour that arises in connective tissue such as bone, muscle<\/span><span data-contrast=\"auto\">\u00a0or around<\/span><span data-contrast=\"auto\">\u00a0sinews.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">We distinguish between\u00a0<\/span><span data-contrast=\"auto\">giant cell tumours<\/span><span data-contrast=\"auto\">\u00a0of the bone and\u00a0<\/span><span data-contrast=\"auto\">giant cell<\/span><span data-contrast=\"auto\">t<\/span><span data-contrast=\"auto\">umors<\/span><span data-contrast=\"auto\">\u00a0in the weekly parts.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">To know with what kind of\u00a0<\/span><span data-contrast=\"auto\">giant cell<\/span><span data-contrast=\"auto\">t<\/span><span data-contrast=\"auto\">umor<\/span><span data-contrast=\"auto\">\u00a0you have to deal with,\u00a0<\/span><span data-contrast=\"auto\">is\u00a0<\/span><span data-contrast=\"auto\">tissue examination is needed. So, in addition to imaging studies (scans), it is usually necessary to take a sample of the tumour, a biopsy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_1 et_pb_row_inner et_block_row\"><div class=\"et_pb_column_inner_1 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_blurb_0 et_pb_blurb et_pb_bg_layout_light et_pb_blurb_position_top et_pb_module et_block_module\"><div class=\"et_pb_blurb_content\"><div class=\"et_pb_blurb_container\"><\/div><\/div><\/div><div class=\"et_pb_toggle_0 et_pb_toggle et_pb_toggle_item et_pb_toggle_close et_pb_module et_block_module\" id=\"toggle2\"><h5 class=\"et_pb_toggle_title\">Connective tissue<\/h5><div class=\"et_pb_toggle_content clearfix\"><p><span><strong>Connective tissue <\/strong>is the body's support tissue and has the following functions: protection of vital organs, strengthening of the body (bones or bone), shock absorber in joints (cartilage), insulation of the body (fatty tissue) and movement (muscles and tendons). Blood vessels and nerves are also partly composed of connective tissue.<\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_2 et_pb_row_inner et_block_row\" id=\"watisreusceltumorbot\"><div class=\"et_pb_column_inner_2 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_3 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\" id=\"#toggle1\"><div class=\"et_pb_text_inner\"><h2>What is a giant cell tumour of the bone?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_1 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><div class=\"et_pb_text_4 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p><span data-contrast=\"auto\" style=\"font-size: 15px;\"><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"NormalTextRun SCXW107683609 BCX0\">This tumour is also called a<span>\u00a0<\/span><\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"SpellingError SCXW107683609 BCX0\">osteoclastoma<\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"NormalTextRun SCXW107683609 BCX0\"><span>\u00a0<\/span>mentioned. A<span>\u00a0<\/span><\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"SpellingError SCXW107683609 BCX0\">giant cell tumour<\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"NormalTextRun SCXW107683609 BCX0\"><span>\u00a0<\/span>of the bone consists of oval cells with so-called giant cells between them (large cells with very many nuclei - where a cell normally has only one nucleus), hence the name. This type of tumour can affect the bone very severely and grows on into the surrounding area with fine offshoots (infiltrative growth), so it can rapidly recur if not completely removed. This is a benign tumour, meaning that in principle it does not spread to other sites. Nevertheless, metastases are seen in about 2% of patients<span>\u00a0<\/span><\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"SpellingError SCXW107683609 BCX0\">origin<\/span><\/span><span data-contrast=\"auto\" class=\"TextRun SCXW107683609 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"NormalTextRun SCXW107683609 BCX0\"><span>\u00a0<\/span>in the lungs on average after 3 to 4 years. These metastases usually grow very slowly.<\/span><\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_3 et_pb_row_inner et_block_row\" id=\"watisreusceltumorwekedelen\"><div class=\"et_pb_column_inner_3 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_5 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\" id=\"#toggle1\"><div class=\"et_pb_text_inner\"><h2>What is a giant soft tissue cell tumour?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_2 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><div class=\"et_pb_text_6 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p><span data-contrast=\"auto\">The correct English term is Giant\u00a0<\/span><span data-contrast=\"auto\">cell<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">tumour<\/span><span data-contrast=\"auto\">\u00a0or\u00a0<\/span><span data-contrast=\"auto\">tendon<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">sheath<\/span><span data-contrast=\"auto\">, the Dutch-language name is\u00a0<\/span><span data-contrast=\"auto\">Giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0of the tendon sheath. Other names are\u00a0<\/span><span data-contrast=\"auto\">tenosynovial<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">, pigmented\u00a0<\/span><span data-contrast=\"auto\">villonodular<\/span><span data-contrast=\"auto\">\u00a0synovitis.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">These tumours are subdivided according to\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li><span data-contrast=\"auto\"><\/span><span data-contrast=\"auto\">the place where they occur: inside or outside a joint\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\"><\/span><\/li>\n<li><span data-contrast=\"auto\"><\/span><span data-contrast=\"auto\">their growth pattern: localised (a nicely rounded bulb) or diffuse (scattered, without a nice capsule around it).<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\"><\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">The localised form is most common.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Tumours are composed of small cells with giant cells (=cells with very many nuclei, where an ordinary cell has only one nucleus) next to them. Other cells are also mixed in the tumour. These tumours are benign, meaning they will not spread to other parts of your body. However, they can have an aggressive behaviour locally, where they also start to grow into nearby soft tissue and\/or bone. They continue to grow into the surrounding area with small outgrowths, making them relatively likely to return after surgical treatment.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_4 et_pb_row_inner et_block_row\" id=\"waarenbijwie\"><div class=\"et_pb_column_inner_4 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_7 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h2>Where and in whom do giant cell tumours occur?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_3 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_5 et_pb_row_inner et_block_row\"><div class=\"et_pb_column_inner_5 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_tabs_0 et_pb_tabs et_pb_module\"><ul class=\"et_pb_tabs_controls clearfix\"><li class=\"et_pb_tab_nav_item_0 et_pb_tab_nav_item et_pb_tab_0 et_pb_tab_active\"><a class=\"et_pb_tab_nav_item_link\" href=\"#\">Giant cell tumour of the bone<\/a><\/li><li class=\"et_pb_tab_nav_item_1 et_pb_tab_nav_item et_pb_tab_1\"><a class=\"et_pb_tab_nav_item_link\" href=\"#\">Giant cell tumour of the soft tissues<\/a><\/li><\/ul><div class=\"et_pb_all_tabs\"><div class=\"et_pb_tab_0 et_pb_tab clearfix et_pb_active_content et_pb_module et_block_module\"><div class=\"et_pb_tab_content\"><p><span data-contrast=\"auto\">This<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0is very rare, less than 2 people per million people per year develop such a tumour. The\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0represents about 20% of all benign tumours of the bone. Typically, patients are affected between 20 and 45 years of age, and about 10-15% are seen in adolescents with a mature skeleton.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Giant cell tumours<\/span><span data-contrast=\"auto\">\u00a0usually occur at the ends of the long pipe bones, mostly around the knee (distal femur and proximal\u00a0<\/span><span data-contrast=\"auto\">tibia<\/span><span data-contrast=\"auto\">), at the level of the wrist (distal radius) and at the level of the shoulder (proximal\u00a0<\/span><span data-contrast=\"auto\">humerus<\/span><span data-contrast=\"auto\">). A\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0is in many cases located just below the cartilage of a joint, and can sometimes grow into the joint itself. Sometimes the spine is affected.<\/span><\/p>\n<\/div><\/div><div class=\"et_pb_tab_1 et_pb_tab clearfix et_pb_module et_block_module\"><div class=\"et_pb_tab_content\"><p><span data-contrast=\"auto\">The\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0can occur at any age, but is most commonly seen between the ages of 30 and 50, more in women than in men.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">This localised form is most commonly diagnosed in the hand (85%), but also in the wrist, ankle and foot, and knee. It is very rarely seen in the\u00a0<\/span><span data-contrast=\"auto\">elbow<\/span><span data-contrast=\"auto\">\u00a0and the hip.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The diffuse type\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0is most commonly seen in the knee (75%) and hip (15%), but can also occur in the ankle, the\u00a0<\/span><span data-contrast=\"auto\">elbow<\/span><span data-contrast=\"auto\">\u00a0and the shoulder. Very rarely, the tumour is also found in the jaw joint or the small joints of the vertebrae (facets). This type\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0can also develop outside the joints, in the muscles or in the lower skin, and usually around the knee, in the thigh or in the foot.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_6 et_pb_row_inner et_block_row\" id=\"watisdeoorzaak\"><div class=\"et_pb_column_inner_6 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_8 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h2>What is the cause of a giant cell tumour?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_4 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><div class=\"et_pb_text_9 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p><span data-contrast=\"auto\">The cause of the emergence of a\u00a0<\/span><span data-contrast=\"auto\">giant cell tumour<\/span><span data-contrast=\"auto\">\u00a0in the bone is not known.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Also in soft tissue tumours, there is<\/span><span data-contrast=\"auto\">\u00a0no single cause<\/span><span data-contrast=\"auto\">. M<\/span><span data-contrast=\"auto\">and suspects\u00a0<\/span><span data-contrast=\"auto\">That it could be a consequence of a\u00a0<\/span><span data-contrast=\"auto\">combination of genetic factors and possibly an inflammatory response at<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">As a result of trauma.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"et_pb_row_inner_7 et_pb_row_inner et_block_row\" id=\"klachten\"><div class=\"et_pb_column_inner_7 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_10 et_pb_text et_pb_bg_layout_light et_pb_bg_layout_light_hover et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h2>What symptoms does it cause?<\/h2>\n<\/div><\/div><div class=\"et_pb_divider_5 et_pb_divider et_pb_space et_pb_divider_position_top et_pb_module\"><div class=\"et_pb_divider_internal\"><\/div><\/div><div class=\"et_pb_tabs_1 et_pb_tabs et_pb_module\"><ul class=\"et_pb_tabs_controls clearfix\"><li class=\"et_pb_tab_nav_item_2 et_pb_tab_nav_item et_pb_tab_2 et_pb_tab_active\"><a class=\"et_pb_tab_nav_item_link\" href=\"#\">Giant cell tumour of the bone<\/a><\/li><li class=\"et_pb_tab_nav_item_3 et_pb_tab_nav_item et_pb_tab_3\"><a class=\"et_pb_tab_nav_item_link\" href=\"#\">Giant cell tumour of the soft tissues<\/a><\/li><\/ul><div class=\"et_pb_all_tabs\"><div class=\"et_pb_tab_2 et_pb_tab clearfix et_pb_active_content et_pb_module et_block_module\"><div class=\"et_pb_tab_content\"><p><span data-contrast=\"auto\" class=\"TextRun SCXW47219322 BCX0\" xml:lang=\"NL-BE\" lang=\"NL-BE\"><span class=\"NormalTextRun SCXW47219322 BCX0\">You usually experience pain and see swelling. The pain may occur at rest (e.g. at night) or after loading. The more the bone is affected by the tumour, the more pain you will experience because the bone can no longer handle the load. Sometimes a spontaneous fracture of the bone occurs because the bone is so fiercely weakened. Deformities in a joint may make it harder for you to move this joint.<\/span><\/span><span class=\"EOP SCXW47219322 BCX0\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><div class=\"et_pb_tab_3 et_pb_tab clearfix et_pb_module et_block_module\"><div class=\"et_pb_tab_content\"><p><span data-contrast=\"auto\">If it is a localised form, you usually see a painless swelling. This swelling grows slowly over a period of several years.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The diffuse form gives rise to pain, swelling or reduced mobility. If the tumour is in a joint, it may give rise to bleeding or up-and-down swelling of this joint. The deterioration of the bone may also cause premature wear and tear of the joint. These symptoms are usually present for several years.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-85","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/pages\/85","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/comments?post=85"}],"version-history":[{"count":1,"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/pages\/85\/revisions"}],"predecessor-version":[{"id":175,"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/pages\/85\/revisions\/175"}],"wp:attachment":[{"href":"https:\/\/www.reusceltumor-cumcura.be\/en\/wp-json\/wp\/v2\/media?parent=85"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}